GenomeComb

exportplink

Format

cg exportplink ?options? varfile resultfilebase

Summary

make a plink "Transposed fileset" from the genome data

Description

This command makes two files that can be used as a transposed fileset in plink (--tfile option).

resultfilebase.tfam.pre
This file must be edited and renamed to resultfilebase.tfam: Only the names are correct. The other fields (father, mother, sex, phenotype) are set to missing (0 or -9) and must be corrected.
resultfilebase.tped
This file contains the variant and the genotype information. Variants with more than two alleles (which are not supported by plink) are skipped with a warning message. The genetic location is (very roughly) estimated by dividing the base position by 1M.

Variant genotypes for samples that have a "u" (unsequenced) in the sequenced field (or in the zyg field if no sequenced filed is present) are set to 0 (unknown genotype) in the plink file.

Use with plink

Edit resultfilebase.tfam.pre to the correct settings, and rename to resultfilebase.tfam You can use the files with the -tfile option, e.g. plink --tfile resultfilebase --recode12

You can use plink to recode to the default plink format (non-tansposed) plink --tfile resultfilebase --recode

Arguments

varfile
variant file
resultfilebase
result file

Options

-q query
query (as can be given to cg_select). Only variants matching the query are included in the result.
-c 1/0
code genotypes to numbers (reference = 1, alternative allele = 2).
-samples samples
Only write data for the given samples to the file, if a sample is not present in the varfile, all genotypes will be set to 0
-all 0/1
Also include genotypes of samples that have a "u" in the sequenced or zyg field. Default is 0, but if no sequenced or zyg field is present in the file, it is 1 (i.e. all genotypes are included)

Category

Analysis